| Bioactivity | [D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats[1][2]. | ||||||
| Invitro | [D-Trp34]-Neuropeptide Y has pKi values of 6.49, 5.43, 7.08, 7.53, 6.55, 5.95, 6.85, 7.41 for hY1, hY2, hY4, hY5, rY1, rY2, rY4, rY5 in CHO cells. [D-Trp34]-Neuropeptide Y has pEC50 values of 6.44, <6, 6.28，7.82 for rY1, rY2 in CHO cells and rY4, rY5 in HEK-293 cells[1]. | ||||||
| Name | [D-Trp34]-Neuropeptide Y | ||||||
| CAS | 153549-84-9 | ||||||
| Shortening | YPSKPDNPGEDAPAEDLARYYSALRHYINLITR-{D-Trp}-RY-NH2 | ||||||
| Formula | C196H289N55O56 | ||||||
| Molar Mass | 4311.72 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
[D-Trp34]-Neuropeptide Y
CAS: 153549-84-9 F: C196H289N55O56 W: 4311.72
-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. -Neuropeptide Y is a significantly l
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